Medical hypnosis mitigates laboratory dyspnoea in healthy humans: a randomised, controlled experimental trial - Neurophysiologie Respiratoire Expérimentale et Clinique Accéder directement au contenu
Article Dans Une Revue European Respiratory Journal Année : 2024

Medical hypnosis mitigates laboratory dyspnoea in healthy humans: a randomised, controlled experimental trial

Résumé

Question Dyspnoea persisting despite treatments of underlying causes requires symptomatic approaches. Medical hypnosis could provide relief without the untoward effects of pharmacological approaches. We addressed this question through experimentally induced dyspnoea in healthy humans (inspiratory threshold loading –excessive inspiratory effort– and carbon dioxide stimulation –air hunger–) Material and Methods 20 volunteers (10 women, 21–40) were studied on 4 separate days. The order of the visits was randomised in two steps, firstly “inspiratory threshold loading first” versus “carbon dioxide first” group (n=10 in each group), secondly “medical hypnosis first” versus “visual distraction first” subgroup (n=5 in each subgroup). Each visit comprised three 5-minutes periods (reference, intervention, washout) during which participants used visual analog scales to rate dyspnoea's sensory and affective dimensions and after which they completed the Multidimensional Dyspnea Profile. Results Medical hypnosis reduced both dimensions of dyspnoea significantly more than visual distraction (inspiratory threshold loading: sensory reduction after 5 min 34% of full VAS versus 8% –p=0.0042–; affective reduction 17.6% versus 2.4% –p=0.044–; carbon dioxide; sensory reduction after 5 min 36.9% versus 3% –p=0.0015–; affective reduction 29.1% versus 8.7% –p=0.0023–). The Multidimensional Dyspnea Profile showed more marked sensory effects during inspiratory threshold loading and more marked affective effects during carbon dioxide stimulation. Answer to the question Medical hypnosis was more effective than visual distraction at attenuating the sensory and affective dimensions of experimentally induced dyspnoea. This provides a strong rationale for clinical studies of hypnosis in persistent dyspnoea patients.
Fichier principal
Vignette du fichier
ERJ_2024_Morélot-Panzini.pdf (3.25 Mo) Télécharger le fichier
Origine Fichiers produits par l'(les) auteur(s)

Dates et versions

hal-04646889 , version 1 (12-07-2024)

Identifiants

Citer

Capucine Morélot-Panzini, Cécile Arveiller-Carvallo, Isabelle Rivals, Nicolas Wattiez, Sophie Lavault, et al.. Medical hypnosis mitigates laboratory dyspnoea in healthy humans: a randomised, controlled experimental trial. European Respiratory Journal, 2024, pp.2400485. ⟨10.1183/13993003.00485-2024⟩. ⟨hal-04646889⟩
0 Consultations
0 Téléchargements

Altmetric

Partager

Gmail Mastodon Facebook X LinkedIn More